When you pour a glass of wine, count to four with “Mississippi” and stop. Each count should equal approximately ½ ounce of alcohol, which should fill the 2-ounce side of a jigger. A standard 750 ml bottle of wine weighs 25.3 ounces, so it will yield five glasses of wine. However, if you're not pouring regular 5-ounce glasses, the amount of wine you get from the bottle will depend on the size of the glass.
The USDA recommends that a glass of wine should weigh 5 ounces. In most cases, people tend to serve a bit more when pouring at home. So, on average, you can expect to get four glasses of wine from a 750 ml bottle. If you pour all the glasses at once, you may even get six glasses out of it.
If you have an exclusive bottle, check out our post on wine bottle sizes. For similar calculations with liquor bottles, read our publication on alcohol bottle sizes. To make sure you get the most out of your bottle, pour it into one of my glasses - they're a bit bigger!.